Tomatoes can fight stomach cancer

Login   |  Register Now

Follow us with

Tomatoes can fight stomach cancer

Posted on : Monday 15th of May 2017

Total 1 News Image

Tomato extracts can inhibit the growth and malignant cloning of stomach cancer cells, according to a new study that paves the way for novel therapies to treat the deadly disease. Researchers analysed whole tomato extracts for their ability to tackle gastric cancer cell lines.

"Their antitumoral effect seem not related to specific components, such as lycopene, but rather suggest that tomatoes should be considered in their entirety," said Daniela Barone, researcher at the Oncology Research Centre of Mercogliano (CROM) in Italy.

Extracts of San Marzano and Corbarino tomato varieties were able to inhibit the growth and cloning behaviour of malignant cells. Treatment with the whole tomato extracts affected key processes within the cells hindering their migration ability, arresting cell cycle through the modulation of retinoblastoma family proteins and specific cell cycle inhibitors, and ultimately inducing cancer cell death through apoptosis.

"Our results prompt further assessment of the potential use of specific nutrients not only in the cancer prevention setting but also as a supportive strategy along with conventional therapies," said Antonio Giordano, professor at the University of Siena in Italy.

"Distinct species may exert different effects, in different stages of a certain neoplasm," said Barone. Gastric cancer is the fourth most common type of cancer worldwide and has been associated with genetic causes, Helicobacter pylori infection, and eating habits such as consumption of smoked and salted food.

Tomatoes are consumed worldwide and are a staple of the Mediterranean diet, which is popularly thought to lower cancer risk.

Various tomato components have also been analysed for their ability to counteract tumour growth in experimental systems, although few studies have analysed the effects of tomatoes in their entirety.

The research was published in the `Journal of Cellular Physiology'.

Disclaimer: The contents or any information provided here is strictly personal and way4indians.com does not hold any responsibility or liability on them. We shall endeavor to upload/publish as many of the comments that are submitted as possible within a reasonable span of time, but we do not guarantee that all comments that are submitted will be uploaded/published. Messages that harass, abuse or threaten other members; have obscene, unlawful, defamatory, libelous, hateful, or otherwise objectionable content; or have spam, commercial or advertising content or links are liable to be removed by the editors. We also reserve the right to edit the comments that do get published. Please do not post any private information unless you want it to be available publicly.

Advertisements

Copyright © 2012-2018, All rights Reserved   |  www.way4indians.com  |  This Logo is a trademark of Way4Indians. For Enquires, please contact : info@way4indians.com